Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9789912 | 0.98 | MCL1 (0.58) | MCL1KCNH2KDM4EHPGDL3MBTL1 | |
| SCHEMBL29587413 | 0.87 | TTR (0.52) | MCL1KCNH2KDM4EHPGDL3MBTL1 | |
| SCHEMBL6045428 | 0.87 | TTR (0.52) | MCL1KCNH2KDM4EHPGDL3MBTL1 | |
| SCHEMBL15619119 | 0.85 | KCNH2 (0.56) | KCNH2HPGDL3MBTL1ALDH1A1HTT | |
| SCHEMBL114250 | 0.85 | KMT2A (0.60) | KCNH2KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL30608270 | 0.84 | NPC1 (0.66) | KCNH2KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL25472764 | 0.83 | KCNH2 (0.58) | KCNH2KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL353910 | 0.83 | KCNH2 (0.58) | KCNH2KDM4EHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL992866 | 0.83 | KCNH2 (0.58) | KCNH2HPGDL3MBTL1ALDH1A1HTT | |
| SCHEMBL28392940 | 0.83 | NPC1 (0.60) | MCL1KCNH2KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138479-B | Tricyclohexyltin 3-methylbenzofuran-2-formate complex and preparation method and application thereof | 衡阳师范学院 | 2023-07-28 | — | — | CN | claimed |
| CN-116082353-A | Preparation method of dihydrobenzofuran spiro-pyrrolidone | 浙江工业大学 | 2023-05-09 | — | — | CN | claimed |
| CN-109694343-B | Decarboxylation method of heterocyclic carboxylic acid compounds | 帕潘纳(北京)科技有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-106748604-B | Method for synthesizing mono-iodo aromatic hydrocarbon or di-iodo aromatic hydrocarbon based on decarboxylation of aromatic carboxylic acid | 湘潭大学 | 2020-06-05 | — | — | CN | claimed |
| CN-111138479-A | Tricyclohexyltin 3-methylbenzofuran-2-formate complex as well as preparation method and application thereof | 衡阳师范学院 | 2020-05-12 | — | — | CN | claimed |
| CN-111138475-A | Tri (2-methyl-2-phenylpropyl) tin 3-methylbenzofuranformate complex and preparation method and application thereof | 衡阳师范学院 | 2020-05-12 | — | — | CN | claimed |
| CN-109694343-A | A kind of heterocyclic carboxylic acid class compound it is decarboxylation method used | 帕潘纳(北京)科技有限公司 | 2019-04-30 | — | — | CN | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| CN-107188846-A | A kind of synthetic method of arylseleno heterocyclic compound | 温州医科大学 | 2017-09-22 | — | — | CN | claimed |
| CN-106748604-A | A kind of method for synthesizing single iodo aromatic hydrocarbon or two iodo aromatic hydrocarbons based on aromatic carboxylic acid's decarboxylic reaction | 湘潭大学 | 2017-05-31 | — | — | CN | claimed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1153022-A4 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | claimed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | claimed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | claimed |
| EP-1153022-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-14 | — | — | EP | claimed |
| WO-2001070232-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-27 | — | — | WO | claimed |
| WO-2001034566-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034155-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2000049011-A1 | PROTHEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-24 | — | — | WO | claimed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | MCL1 1905/4885KCNH2 977/4885KDM4E 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.