Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130053 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL18388007 | 0.88 | SLC6A1 (0.42) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL18498636 | 0.84 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7226282 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7234667 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL23386481 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL28807483 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7234198 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7225571 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7225569 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682537-B1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC (US) | 2012-03-28 | — | — | EP | disclosed |