Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.49 |
| ▸ | PPARA | Q07869 | 12/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795234 | 0.85 | FFAR1 (0.62) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL8794339 | 0.84 | FFAR1 (0.60) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL5086395 | 0.83 | PPARG (0.51) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL7162936 | 0.83 | FFAR1 (0.59) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL7162039 | 0.82 | PPARG (0.49) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL7164834 | 0.82 | FFAR1 (0.58) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL5086402 | 0.80 | PPARG (0.49) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8795246 | 0.78 | KDR (0.59) | PPARGPPARAFFAR1KDR | |
| SCHEMBL7164855 | 0.78 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL8128489 | 0.77 | PPARG (0.50) | PPARGPPARAFFAR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612743-B1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-10 | — | — | EP | disclosed |