Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794644 | 0.91 | ALDH1A1 (0.59) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8793850 | 0.90 | MAPT (0.57) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL7394553 | 0.88 | MAPT (0.62) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8793166 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8792742 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8794888 | 0.86 | MEN1 (0.41) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL7546948 | 0.86 | MEN1 (0.57) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8794642 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL8794682 | 0.85 | MAPT (0.59) | ALDH1A1MAPTCYP2C19KMT2AMEN1 | |
| SCHEMBL7398670 | 0.85 | MAPT (0.66) | ALDH1A1MAPTCYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492485-B1 | N-Acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same | GYOGYSZERKUTATO INTEZET (HU) | 1997-11-19 | — | — | EP | disclosed |
| US-5639751-A | N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders | CYOGYSZERKUTATO INTEZET KFT (HU) | 1997-06-17 | — | — | US | disclosed |
| US-5604223-A | TREATING EPILEPSY, NERVOUS SYSTEM DISORDER | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1997-02-18 | — | — | US | disclosed |
| US-5536832-A | CENTRAL NERVOUS SYSTEM DISORDERS | GYOGYSZERKUTATO INTEZET KFT (HU) | 1996-07-16 | — | — | US | disclosed |
| US-5521174-A | ANTISPASMODIC AGENTS | GYOGYSZERKUTATO INTEZET KV. (HU) | 1996-05-28 | — | — | US | disclosed |
| US-5519019-A | NERVOUS SYSTEM DISORDERS AND MUSCLE RELAXANTS | GYOGYSZERKUTATO INTEZET (HU) | 1996-05-21 | — | — | US | disclosed |
| US-5459137-A | Muscle relaxants, anticonvulsants, neuroprotective agents | GYOGYSZERKU-TATO INTEZET KFT (HU) | 1995-10-17 | — | — | US | disclosed |
| EP-0492485-A1 | N-Acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same | GYOGYSZERKUTATO INTEZET (HU) | 1992-07-01 | — | — | EP | disclosed |