Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795310 | 0.92 | AURKA (0.44) | MEN1KMT2AAURKAEGFRPDGFRB | |
| SCHEMBL8796312 | 0.91 | AURKA (0.49) | AURKAEGFRPDGFRBRPS6KB1HTT | |
| SCHEMBL8796051 | 0.90 | MEN1 (0.43) | MEN1KMT2AAURKAEGFRPDGFRB | |
| SCHEMBL8795881 | 0.90 | MEN1 (0.44) | MEN1KMT2AAURKAEGFRPDGFRB | |
| SCHEMBL8796500 | 0.88 | MEN1 (0.46) | MEN1KMT2AEGFRPDGFRBERBB2 | |
| SCHEMBL8825753 | 0.86 | MEN1 (0.60) | MEN1KMT2AEGFRHTTALDH1A1 | |
| SCHEMBL8796516 | 0.84 | MAPK1 (0.47) | EGFRPDGFRBHTTALDH1A1KDM4E | |
| SCHEMBL8825757 | 0.84 | KDM4E (0.51) | MEN1KMT2AEGFRERBB2HTT | |
| SCHEMBL8796096 | 0.84 | RPS6KB1 (0.46) | MEN1KMT2AAURKAEGFRPDGFRB | |
| SCHEMBL8795890 | 0.83 | PIK3CA (0.47) | MEN1KMT2AAURKAEGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758653-A1 | IMIDAZOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |