Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482499 | 0.93 | CYP2D6 (0.67) | MEN1KMT2AALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8487591 | 0.92 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1PKMCYP2D6 | |
| SCHEMBL8794686 | 0.89 | CYP2D6 (0.53) | MEN1KMT2ACYP2D6CYP2C9CYP3A4 | |
| SCHEMBL8795789 | 0.89 | MEN1 (0.61) | MEN1KMT2ACYP2D6CYP2C9CYP3A4 | |
| SCHEMBL8795193 | 0.89 | CYP2D6 (0.53) | MEN1KMT2ACYP2D6CYP2C9CYP3A4 | |
| SCHEMBL8483983 | 0.89 | CYP2D6 (0.55) | MEN1KMT2AALDH1A1PKMCYP2D6 | |
| SCHEMBL8487067 | 0.89 | MAPT (0.56) | MEN1KMT2AALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL8795018 | 0.88 | CYP2D6 (0.52) | MEN1KMT2ACYP2D6CYP2C9CYP3A4 | |
| SCHEMBL8484029 | 0.88 | CYP2D6 (0.54) | MEN1KMT2AALDH1A1PKMCYP2D6 | |
| SCHEMBL8525293 | 0.88 | CYP2D6 (0.51) | MEN1KMT2ACYP2D6CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |