Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATF4 | P18848 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8487010 | 0.98 | POLB (0.59) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL4202083 | 0.84 | CYP19A1 (0.63) | POLBTDP1BLMMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8795178 | 0.82 | CYP19A1 (0.60) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL4207158 | 0.81 | POLB (0.60) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL4203506 | 0.78 | CYP3A4 (0.69) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL8482951 | 0.75 | RAB9A (0.56) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL4205316 | 0.75 | POLB (0.60) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL12615985 | 0.74 | NOTUM (0.78) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL8381009 | 0.73 | NOTUM (0.51) | POLBTDP1BLMMAPTALDH1A1 | |
| SCHEMBL17019881 | 0.73 | POLB (0.78) | POLBTDP1BLMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |