Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318810 | 0.87 | SRD5A1 (0.43) | SRD5A1SRD5A2 | |
| SCHEMBL13611192 | 0.85 | SRD5A1 (0.40) | SRD5A1SRD5A2 | |
| SCHEMBL13603641 | 0.85 | SRD5A1 (0.40) | SRD5A1SRD5A2 | |
| SCHEMBL4176860 | 0.85 | AR (0.40) | — | |
| SCHEMBL14544277 | 0.85 | AR (0.40) | — | |
| SCHEMBL13604101 | 0.85 | AR (0.40) | — | |
| SCHEMBL7621273 | 0.84 | SRD5A1 (0.39) | SRD5A1SRD5A2 | |
| SCHEMBL7616401 | 0.83 | AR (0.58) | SRD5A2 | |
| SCHEMBL14504017 | 0.83 | AR (0.58) | SRD5A2 | |
| SCHEMBL8536963 | 0.83 | AKR1B10 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607400-B1 | Fluorinated 17-beta substituted-4-aza-5-alpha- andostran-3one derivatives. | PHARMACIA & UPJOHN SPA (IT) | 1997-11-05 | — | — | EP | disclosed |
| US-5407939-A | Inhibitors of androgen action by means of testosterone 5alpha-reductase inhibition | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-04-18 | — | — | US | disclosed |
| WO-1994003475-A1 | FLUORINATED 17β-SUBSTITUTED 4-AZA-5α-ANDROSTAN-3-ONE DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-02-17 | — | — | WO | disclosed |