Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795577 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8795144 | 0.85 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL8795475 | 0.84 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8794799 | 0.83 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL8794636 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL9376299 | 0.78 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL8794705 | 0.77 | RARA (0.35) | SMN1; SMN2 | |
| SCHEMBL8794632 | 0.76 | BACE1 (0.35) | SMN1; SMN2 | |
| SCHEMBL8793777 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL8793143 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586405-B1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF LILLY GMBH (DE) | 1997-09-10 | — | — | EP | disclosed |
| EP-0586405-A1 | NOVEL 2H-BENZO b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS. | BEIERSDORF LILLY GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020671-A1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF-LILLY GMBH (DE) | 1992-11-26 | — | — | WO | disclosed |