Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9077430 | 1.00 | PREP (0.41) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL8838990 | 0.88 | L3MBTL1 (0.44) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL8900608 | 0.87 | KLK7 (0.41) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL19499310 | 0.87 | KLK7 (0.41) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL8795737 | 0.86 | L3MBTL1 (0.42) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL9078167 | 0.86 | L3MBTL1 (0.47) | PREPKLK7KLK5MEN1KMT2A | |
| SCHEMBL9079150 | 0.85 | KLK7 (0.38) | PREPKLK7KLK5L3MBTL1AGTR2 | |
| SCHEMBL9092835 | 0.83 | PRCP (0.40) | PREPKLK7KLK5L3MBTL1HTR2C | |
| SCHEMBL9037725 | 0.82 | L3MBTL1 (0.39) | PREPKLK7KLK5L3MBTL1AGTR2 | |
| SCHEMBL19506208 | 0.81 | TMEM97 (0.38) | PREPKLK7KLK5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659180-B1 | ANTI-VIRAL SULFUR-ANALOGUES OF 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL (DEOXYNOJIRIMYCIN) | SEARLE & CO (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5639882-A | CHEMICAL INTERMEDIATES FOR FORMING VIRICIDES INHIBITING LENTIVIRUSES | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637707-A | STEREOSELECTIVELY ADDING ORGANONETALLIC REAGENT BY NUCLEOPHILIC ADDITION TO KETONE COMPOUND | G. D. SEARLE & CO. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0566557-B1 | 2- and 3- amino and azido derivatives of 1,5-iminosugars as antiviral compounds | SEARLE & CO (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5550243-A | ACYLATING DEOXYNOJIRIMYCIN, PROTECTING C-4 AND C-6 HYDROXYLS BY ACETALIZATION OR KETALIZATION, SULFONYLATING HYDROXYL AT C-2, FORMING EPOXIDE AT C-2 AND C-3, OPENING EPOXIDE BY NUCLEOPHILIC ATTACK WITH AZIDE COMPOUND | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0566556-B1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | SEARLE & CO (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5530132-A | VIRICIDES, HIV VIRUS | G. D. SEARLE & CO. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5523406-A | STEREOSPECIFIC ALKYLATION BY NUCLEOPHILIC ADDITION AT C-2 WITH A GRIGNARD REAGENT | G. D. SEARLE & CO. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5502193-A | VIRICIDES FOR AIDS | G. D. SEARLE & CO. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5436341-A | Intermediates for 2,3-diamino-1,5-iminosugars | G. D. SEARLE & CO. (US) | 1995-07-25 | — | — | US | disclosed |
| US-5391746-A | Inhibitors of lentiviruses; deoxynojirimycin derivatives | G. D. SEARLE & CO. (US) | 1995-02-21 | — | — | US | disclosed |
| US-5350854-A | AIDS treatment | G. D. SEARLE & CO. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5342951-A | Inhibiting glycosidase enzymes, antiviral compounds | G.D. SEARLE & CO. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5334717-A | Inhibit lentiviruses | G. D. SEARLE & CO. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5331096-A | Viricides, HIV, enzyme inhibitors | G. D. SEARLE & CO. (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1994005635-A1 | ANTI-VIRAL SULFUR-ANALOGUES OF 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL (DEOXYNOJIRIMYCIN) | G.D. SEARLE & CO. (US) | 1994-03-17 | — | — | WO | disclosed |
| US-5258518-A | Antiviral agents, anti-HIV activity | G. D. SEARLE & CO. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0566557-A1 | 2- and 3- amino and azido derivatives of 1,5-iminosugars as antiviral compounds | G.D. SEARLE & COMPANY (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5216168-A | Lentivirus inhibitors | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |
| US-5206251-A | Viricide | G. D. SEARLE & CO. (US) | 1993-04-27 | — | — | US | disclosed |