Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795330 | 0.76 | NPC1 (0.43) | — | |
| SCHEMBL7411619 | 0.72 | — | — | |
| SCHEMBL8795659 | 0.70 | — | — | |
| SCHEMBL8795166 | 0.65 | — | — | |
| SCHEMBL8795958 | 0.61 | GRIN2D (0.45) | — | |
| SCHEMBL4078284 | 0.61 | PARP1 (1.00) | PARP1 | |
| SCHEMBL12891155 | 0.60 | RAB9A (0.61) | PARP1 | |
| SCHEMBL123584 | 0.60 | RAB9A (0.78) | PARP1 | |
| SCHEMBL29372630 | 0.60 | RAB9A (0.78) | PARP1 | |
| SCHEMBL4045125 | 0.58 | PSEN1 (0.42) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752993-A1 | 1,2,4-TRIAZOLO[4,3-a]PYRAZINE-4-ONE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026351-A1 | 1,2,4-TRIAZOLO[4,3-a]PYRAZINE-4-ONE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | disclosed |