Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302228 | 0.88 | PTH1R (0.41) | PTH1RENPP2ATXN2 | |
| SCHEMBL16302225 | 0.88 | PTH1R (0.42) | PTH1RSLC6A9 | |
| SCHEMBL13552145 | 0.80 | PTH1R (0.56) | PTH1RSLC6A9 | |
| SCHEMBL879732 | 0.80 | PTH1R (0.43) | PTH1R | |
| SCHEMBL16302187 | 0.79 | PTH1R (0.46) | PTH1R | |
| SCHEMBL17346272 | 0.78 | PTH1R (0.55) | PTH1R | |
| SCHEMBL848391 | 0.78 | PTH1R (0.54) | PTH1RSLC6A9 | |
| SCHEMBL847358 | 0.78 | PTH1R (0.57) | PTH1RSLC6A9 | |
| SCHEMBL16358654 | 0.78 | PTH1R (0.46) | PTH1RENPP2ATXN2 | |
| SCHEMBL879653 | 0.78 | PTH1R (0.44) | PTH1RSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |