Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 10/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358680 | 0.88 | PTH1R (0.50) | PTH1RTACR1KDM4EALDH1A1SLC6A9 | |
| SCHEMBL849439 | 0.87 | PTH1R (0.53) | PTH1RTACR1KDM4EALDH1A1SLC6A9 | |
| SCHEMBL849019 | 0.80 | TACR1 (0.57) | PTH1RTACR1KDM4E | |
| SCHEMBL16302187 | 0.78 | PTH1R (0.46) | PTH1RTACR1 | |
| SCHEMBL879649 | 0.78 | PTH1R (0.47) | PTH1RSLC6A9 | |
| SCHEMBL848263 | 0.77 | PTH1R (0.58) | PTH1RTACR1KDM4EALDH1A1SLC6A9 | |
| SCHEMBL16302228 | 0.75 | PTH1R (0.41) | PTH1RALDH1A1 | |
| SCHEMBL13552118 | 0.74 | PTH1R (0.47) | PTH1RTACR1 | |
| SCHEMBL17346272 | 0.74 | PTH1R (0.55) | PTH1R | |
| SCHEMBL16302225 | 0.74 | PTH1R (0.42) | PTH1RSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |