SCHEMBL8796601

SCHEMBL8796601

O=C(C1CC2CCCCC2N1C(=O)CCCc1ccccc1)N1CCCC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PREP P48147 13/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9180223 1.00 PREP (0.66) PREP
SCHEMBL8796594 1.00 PREP (0.66) PREP
SCHEMBL9773813 0.87 ACE (0.55) PREP
SCHEMBL9774258 0.85 ACE (0.53) PREP
SCHEMBL9774332 0.83 MEN1 (0.53) PREP
SCHEMBL9774314 0.83 PREP (0.49) PREP
SCHEMBL9774157 0.83 PREP (0.49) PREP
SCHEMBL9774318 0.82 PREP (0.51) PREP
SCHEMBL5964835 0.82 PREP (0.62) PREP
SCHEMBL5964406 0.82 PREP (0.62) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0541407-B1 Nitrogen containing bicyclic derivatives, method for their preparation and pharmaceutical compositions containing them ADIR (FR) 1997-02-26 EP disclosed
EP-0541407-A1 Nitrogen containing bicyclic derivatives, method for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1993-05-12 EP disclosed