Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.53 |
| ▸ | PREP | P48147 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773813 | 0.97 | ACE (0.55) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL9774174 | 0.96 | ACE (0.52) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL9774278 | 0.92 | ACE (0.54) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL9775243 | 0.88 | EPHX1 (0.51) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL9774157 | 0.88 | PREP (0.49) | ACEPREPMEN1KMT2ANPC1 | |
| SCHEMBL9775200 | 0.88 | CYP1A2 (0.50) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL9774191 | 0.86 | PREP (0.47) | ACEPREPMEN1KMT2ACYP3A4 | |
| SCHEMBL8796594 | 0.85 | PREP (0.66) | PREP | |
| SCHEMBL9180223 | 0.85 | PREP (0.66) | PREP | |
| SCHEMBL8796601 | 0.85 | PREP (0.66) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983623-A | Prolyl endopeptidase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |