Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.74 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.73 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796970 | 0.91 | AVPR1A (0.73) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL6988983 | 0.91 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BMEN1KMT2A | |
| SCHEMBL6993277 | 0.90 | AVPR2 (0.85) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL6991600 | 0.88 | AVPR1A (0.58) | AVPR1AAVPR2AVPR1BMEN1KMT2A | |
| SCHEMBL8797156 | 0.87 | AVPR1A (0.73) | AVPR1AAVPR2AVPR1BMEN1KMT2A | |
| SCHEMBL8796809 | 0.87 | AVPR1A (0.79) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL8801105 | 0.86 | AVPR2 (0.72) | AVPR1AAVPR2AVPR1BALDH1A1LMNA | |
| SCHEMBL6991283 | 0.85 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8797804 | 0.84 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8796903 | 0.84 | AVPR1A (0.74) | AVPR1AAVPR2AVPR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |