Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 12/20 | 0.79 |
| ▸ | AVPR2 | P30518 | 12/20 | 0.79 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | OXTR | P30559 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797804 | 0.88 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8796903 | 0.88 | AVPR1A (0.74) | AVPR1AAVPR2AVPR1BTP53CHRM1 | |
| SCHEMBL6991283 | 0.87 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL8796707 | 0.87 | AVPR1A (0.74) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL8801105 | 0.86 | AVPR2 (0.72) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL8797156 | 0.86 | AVPR1A (0.73) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL8719654 | 0.86 | AVPR2 (0.73) | AVPR1AAVPR2OXTR | |
| SCHEMBL6989046 | 0.85 | AVPR1A (1.00) | AVPR1AAVPR2AVPR1BOXTR | |
| SCHEMBL6993277 | 0.85 | AVPR2 (0.85) | AVPR1AAVPR2AVPR1BLMNATP53 | |
| SCHEMBL8796970 | 0.84 | AVPR1A (0.73) | AVPR1AAVPR2AVPR1BLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |