Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796492 | 0.85 | NPC1 (0.37) | HPGDALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7960414 | 0.84 | ALDH1A1 (0.36) | HPGDALDH1A1APOBEC3AAPOBEC3GEPHX2 | |
| SCHEMBL7949988 | 0.84 | ALDH1A1 (0.36) | HPGDALDH1A1APOBEC3AAPOBEC3GEPHX2 | |
| SCHEMBL8796921 | 0.80 | SMN1; SMN2 (0.36) | HPGDALDH1A1APOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL8796230 | 0.79 | KMT2A (0.34) | HPGDALDH1A1APOBEC3AAPOBEC3GEPHX2 | |
| SCHEMBL8796950 | 0.78 | HPGD (0.37) | HPGDALDH1A1APOBEC3AAPOBEC3GEPHX2 | |
| SCHEMBL8796388 | 0.77 | HPGD (0.35) | HPGDALDH1A1APOBEC3AAPOBEC3GEPHX2 | |
| SCHEMBL7964591 | 0.77 | MAPT (0.38) | HPGDALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL7958051 | 0.77 | ALDH1A1 (0.39) | HPGDALDH1A1TSHR | |
| SCHEMBL7949759 | 0.76 | MAPT (0.40) | HPGDALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |