SCHEMBL8796946

SCHEMBL8796946

C=CCOC(=O)O[C@@H]1CC(=C)C[C@@H]1OC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
KCNA3 P22001 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594654 0.81 ALDH1A1 (0.35) CYP3A4KCNA3
SCHEMBL7594285 0.79
SCHEMBL2329949 0.76 ALDH1A1 (0.37) CYP3A4KCNA3CA1CA2
SCHEMBL2326669 0.71 ALDH1A1 (0.44) CYP3A4KCNA3
SCHEMBL18357173 0.69 BCHE (0.41) CYP3A4
SCHEMBL18357115 0.69 BCHE (0.41) CYP3A4
SCHEMBL11180560 0.69 NR2C2 (0.38) CYP3A4
SCHEMBL19888000 0.69 BCHE (0.41) CYP3A4
SCHEMBL18357139 0.69 BCHE (0.41) CYP3A4
SCHEMBL5599867 0.69 KCNA3 (0.42) CYP3A4KCNA3CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788473-A1 NOVEL HIGH ENANTIO-SELECTIVE PROCESS FOR PRODUCING PURE ENANTIOMERIC CYCLOPENTANE AND CYCLOPENTENE-BETA-AMINO ACIDS BAYER AG (DE) 1997-08-13 EP disclosed
WO-1995019337-A1 NOVEL HIGH ENANTIO-SELECTIVE PROCESS FOR PRODUCING PURE ENANTIOMERIC CYCLOPENTANE AND CYCLOPENTENE-β-AMINO ACIDS BAYER AKTIENGESELLSCHAFT (DE) 1995-07-20 WO disclosed