Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068384 | 0.89 | EDNRB (0.42) | EDNRBEDNRA | |
| SCHEMBL8799145 | 0.74 | TARBP2 (0.31) | — | |
| SCHEMBL7336011 | 0.66 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL7344975 | 0.65 | HSP90AA1 (0.38) | EDNRBEDNRA | |
| SCHEMBL7342903 | 0.62 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL7339610 | 0.60 | HSP90AA1 (0.36) | EDNRBEDNRA | |
| SCHEMBL7068381 | 0.58 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL7065613 | 0.56 | MAPK1 (0.39) | EDNRA | |
| SCHEMBL30832960 | 0.56 | CYP3A4 (0.52) | EDNRBEDNRA | |
| SCHEMBL7069619 | 0.56 | EDNRA (0.43) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811001-A1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-12-10 | — | — | EP | claimed |