SCHEMBL879719

SCHEMBL879719

NC(=O)C1(N)CCNCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
KMT2A Q03164 1/20 0.50
DPP9 Q86TI2 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
DPP4 P27487 1/20 0.37
NEK2 P51955 1/20 0.32
PKM P14618 1/20 0.32
GRM2 Q14416 2/20 0.31
GRM3 Q14832 2/20 0.31
GRM4 Q14833 2/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
MTOR P42345 1/20 0.31
GRM1 Q13255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19641148 0.97 KDM4E (0.48) KDM4EKMT2ADPP9DPP7DPP4
Hydrochloric Acid SCHEMBL7927887 0.83 KDM4E (0.41) KDM4EKMT2ADPP9DPP7DPP4
SCHEMBL31255137 0.83 KDM4E (0.41) KDM4EKMT2ADPP9DPP7DPP4
SCHEMBL31255129 0.83 KDM4E (0.41) KDM4EKMT2ADPP9DPP7DPP4
SCHEMBL413223 0.80
SCHEMBL28600615 0.79 GRM4 (0.45) KDM4EKMT2ADPP9DPP7DPP4
SCHEMBL180209 0.79 GRM4 (0.45) KDM4EKMT2ADPP9DPP7DPP4
Hydrochloric Acid SCHEMBL4765076 0.77
Bromide SCHEMBL9657131 0.77 GRM4 (0.43) KDM4EKMT2ADPP9DPP7DPP4
SCHEMBL4516934 0.77 DPP9 (0.42) KDM4EKMT2ADPP9DPP7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP claimed
CN-119899240-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-04-29 CN claimed
CN-119390765-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-02-07 CN claimed
WO-2024212865-A1 κ OPIOID RECEPTOR AGONIST AND USE THEREOF 成都奥达生物科技有限公司 2024-10-17 WO claimed
CN-118772231-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2024-10-15 CN claimed
CN-115043904-B Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2024-07-23 CN claimed
CN-115043904-A Long-acting K opioid receptor agonist 成都奥达生物科技有限公司 2022-09-13 CN claimed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP disclosed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 EP disclosed
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 EP disclosed
CN-119899240-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-04-29 CN disclosed
CN-119390765-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-02-07 CN disclosed
WO-2024212865-A1 κ OPIOID RECEPTOR AGONIST AND USE THEREOF 成都奥达生物科技有限公司 2024-10-17 WO disclosed
EP-0721452-B1 PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE MALLINCKRODT INC (US) 2001-06-20 EP disclosed
EP-0854869-A1 SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1998-07-29 EP disclosed
US-5739336-A SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS SYNTEX (U.S.A.) INC. (US) 1998-04-14 US disclosed
WO-1997011940-A1 SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1997-04-03 WO disclosed
WO-1997000872-A1 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 1997-01-09 WO disclosed
EP-0721452-A1 PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE Mallinckrodt Chemical, Inc. (US) 1996-07-17 EP disclosed
WO-1995009152-A1 PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE MALLINCKRODT CHEMICAL, INC. (US) 1995-04-06 WO disclosed