SCHEMBL8797258

SCHEMBL8797258

CCOc1cc2c(cc1OCC)C(c1ccccc1)NC(CC)(CC(=O)CC)CS2

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8689617 1.00 SLC10A2 (0.42) SLC10A2
SCHEMBL8245823 0.91 SLC10A2 (0.48) SLC10A2
SCHEMBL8245819 0.91 SLC10A2 (0.48) SLC10A2
SCHEMBL8615850 0.86 SLC10A2 (0.37) SLC10A2
SCHEMBL8615846 0.86 SLC10A2 (0.37) SLC10A2
SCHEMBL9284370 0.85 SLC10A2 (0.44) SLC10A2
SCHEMBL8797837 0.83 SLC10A2 (0.42) SLC10A2
SCHEMBL8689816 0.83 SLC10A2 (0.42) SLC10A2
SCHEMBL7477854 0.82 SLC10A2 (0.38) SLC10A2
SCHEMBL7477850 0.82 SLC10A2 (0.38) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP claimed
WO-1994018183-A1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO claimed
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP disclosed
EP-0683773-A1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES. WELLCOME FOUND (GB) 1995-11-29 EP disclosed
WO-1994018183-A1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO disclosed