Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798886 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8797528 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8993287 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8797500 | 0.86 | ITGB3 (0.66) | ITGB3ITGA2BKDM4EF2 | |
| SCHEMBL8797225 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8798205 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8797941 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8797842 | 0.80 | ITGB3 (0.67) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL8798079 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| SCHEMBL1387801 | 0.79 | ITGB3 (0.73) | ITGB3ITGA2BKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708775-B1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1997-05-28 | — | — | EP | claimed |
| EP-0708775-A1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1996-05-01 | — | — | EP | claimed |
| EP-0708775-B1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5493020-A | ANTICOAGULANTS | GENENTECH, INC. (US) | 1996-02-20 | — | — | US | disclosed |