Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850619 | 0.90 | PTH1R (0.36) | PTH1RGRIN2BPDK2 | |
| SCHEMBL850616 | 0.90 | PTH1R (0.36) | PTH1RGRIN2BPDK2 | |
| SCHEMBL850618 | 0.90 | PTH1R (0.36) | PTH1RGRIN2BPDK2 | |
| SCHEMBL850617 | 0.90 | PTH1R (0.36) | PTH1RGRIN2BPDK2 | |
| SCHEMBL848946 | 0.84 | PTH1R (0.34) | PTH1R | |
| SCHEMBL848945 | 0.84 | PTH1R (0.34) | PTH1R | |
| SCHEMBL880096 | 0.82 | PTH1R (0.38) | PTH1R | |
| SCHEMBL848925 | 0.80 | PTH1R (0.34) | PTH1RGRIN2BPDK2 | |
| SCHEMBL848926 | 0.80 | PTH1R (0.34) | PTH1RGRIN2BPDK2 | |
| SCHEMBL847601 | 0.78 | PTH1R (0.39) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | disclosed |
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |