Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.72 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798937 | 0.91 | ITGB3 (0.73) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8798139 | 0.90 | ITGB3 (0.69) | ITGB3ITGA2BITGA2F2F10 | |
| SCHEMBL8798242 | 0.90 | ITGB3 (0.69) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8798644 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8797347 | 0.88 | ITGB3 (0.69) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8797941 | 0.85 | ITGB3 (0.70) | ITGB3ITGA2BKDM4E | |
| SCHEMBL8992929 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EF2F10 | |
| SCHEMBL8992972 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL7427864 | 0.83 | ITGB3 (0.70) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8797500 | 0.82 | ITGB3 (0.66) | ITGB3ITGA2BITGA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708775-B1 | TRICYCLIC INHIBITORS OF THE GPII b III a RECEPTOR | GENENTECH INC (US) | 1997-05-28 | — | — | EP | claimed |
| US-5493020-A | ANTICOAGULANTS | GENENTECH, INC. (US) | 1996-02-20 | — | — | US | disclosed |