Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798465 | 0.85 | NPC1 (0.32) | NPC1RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL8563298 | 0.75 | NMT1 (0.33) | LMNACCR4NPSR1 | |
| SCHEMBL8798497 | 0.75 | TSHR (0.37) | LMNACCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL9642094 | 0.75 | JAK1 (0.35) | JAK1ADORA3ADORA2AADORA1 | |
| SCHEMBL8136597 | 0.71 | MEN1 (0.36) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7852586 | 0.70 | CCR4 (0.36) | CCR4ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8798546 | 0.69 | CCR4 (0.35) | CCR4 | |
| SCHEMBL7853634 | 0.68 | CCR4 (0.34) | CCR4 | |
| SCHEMBL9176758 | 0.64 | CCR4 (0.42) | KDM4EHSD17B10LMNACCR4ALDH1A1 | |
| SCHEMBL8883188 | 0.64 | NPSR1 (0.34) | LMNACCR4KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537423-B1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0537423-A1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DowElanco (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5201938-A | N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1993-04-13 | — | — | US | disclosed |