Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 14/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853634 | 0.82 | CCR4 (0.34) | CCR4NMT1 | |
| SCHEMBL8563298 | 0.79 | NMT1 (0.33) | CCR4NMT1 | |
| SCHEMBL9536404 | 0.78 | CCR4 (0.38) | CCR4 | |
| SCHEMBL9185284 | 0.77 | CCR4 (0.51) | CCR4EDNRA | |
| SCHEMBL8798497 | 0.77 | TSHR (0.37) | CCR4NMT1 | |
| SCHEMBL8848553 | 0.76 | CCR4 (0.39) | CCR4 | |
| SCHEMBL8556082 | 0.76 | CCR4 (0.41) | CCR4 | |
| SCHEMBL9182478 | 0.75 | CCR4 (0.47) | CCR4 | |
| SCHEMBL8901312 | 0.75 | PTGS2 (0.34) | CCR4 | |
| SCHEMBL8560163 | 0.75 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537423-B1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-10-08 | — | — | EP | claimed |
| EP-0537423-A1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DowElanco (US) | 1993-04-21 | — | — | EP | claimed |
| US-5201938-A | N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1993-04-13 | — | — | US | claimed |
| EP-0537423-B1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0537423-A1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DowElanco (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5201938-A | N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1993-04-13 | — | — | US | disclosed |