Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.44 |
| ▸ | ITGAV | P06756 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815155 | 1.00 | KMT2A (0.57) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL5858099 | 0.91 | KMT2A (0.62) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL5847407 | 0.87 | KMT2A (0.56) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL5847401 | 0.87 | KMT2A (0.56) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL5847436 | 0.84 | KMT2A (0.55) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL5847398 | 0.83 | KMT2A (0.54) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL6219736 | 0.83 | KMT2A (0.54) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL20379845 | 0.82 | PTGS1 (0.59) | KMT2AMAPK9ALDH1A1KDM4EMCL1 | |
| SCHEMBL6220378 | 0.81 | KMT2A (0.53) | KMT2AMAPK9ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6265628 | 0.81 | RAB9A (0.52) | KMT2AMAPK9ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996039386-A1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |