Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798466 | 1.00 | HPGD (0.49) | HPGDGAAALDH1A1LMNAMAPT | |
| SCHEMBL8798476 | 0.92 | GAA (0.41) | HPGDGAAALDH1A1LMNAMAPT | |
| SCHEMBL8797673 | 0.86 | HPGD (0.52) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8797670 | 0.86 | HPGD (0.52) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8797917 | 0.86 | HPGD (0.52) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8797922 | 0.86 | HPGD (0.52) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8796650 | 0.85 | MAPT (0.42) | ALDH1A1LMNAMAPTHRH3 | |
| SCHEMBL7454718 | 0.84 | MGAM (0.58) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8796772 | 0.84 | MGAM (0.58) | HPGDGAAMGAMSIMGAM2 | |
| SCHEMBL8797738 | 0.80 | HPGD (0.52) | HPGDGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |