Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798469 | 0.92 | HPGD (0.49) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8798466 | 0.92 | HPGD (0.49) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8797928 | 0.86 | PSEN1 (0.44) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8797677 | 0.86 | CSNK2A2 (0.51) | MEN1POLBKMT2AHPGDCSNK2A2 | |
| SCHEMBL8796784 | 0.84 | MGAM (0.46) | GAAMGAMSIMGAM2HPGD | |
| SCHEMBL8796650 | 0.84 | MAPT (0.42) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL8796699 | 0.81 | CSNK2A2 (0.51) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8797746 | 0.81 | CSNK2A2 (0.43) | GAAMGAMSIMGAM2HPGD | |
| SCHEMBL8797031 | 0.80 | MGAM (0.45) | GAAMGAMSIMGAM2HPGD | |
| SCHEMBL8796673 | 0.78 | HRH3 (0.47) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |