SCHEMBL8798671

SCHEMBL8798671

CC(=O)Oc1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.85
POLB P06746 2/20 0.85
PKM P14618 1/20 0.85
ELANE P08246 3/20 0.59
ALDH1A1 P00352 3/20 0.56
HSP90AA1 P07900 1/20 0.56
GAA P10253 1/20 0.56
LMNA P02545 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PTGS2 P35354 2/20 0.52
HTR6 P50406 1/20 0.52
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9343618 0.92 PKM (1.00) MAPTPOLBPKMELANEALDH1A1
SCHEMBL12123501 0.89 MAPT (0.72) MAPTPOLBPKMELANEALDH1A1
SCHEMBL14700494 0.85 PKM (0.85) MAPTPOLBPKMELANEGAA
SCHEMBL14227007 0.85 PKM (0.85) MAPTPOLBPKMELANEALDH1A1
SCHEMBL25703273 0.85 MAPT (0.61) MAPTPOLBPKMELANEALDH1A1
SCHEMBL9481091 0.85 PKM (0.60) MAPTPOLBPKMELANEALDH1A1
SCHEMBL16027098 0.82 PKM (0.73) MAPTPOLBPKMELANEALDH1A1
SCHEMBL1687670 0.81 MAPT (0.60) MAPTPOLBPKMELANEALDH1A1
SCHEMBL8461136 0.81 MAPT (0.56) MAPTPOLBPKMELANEALDH1A1
SCHEMBL13133214 0.81 PKM (0.77) MAPTPOLBPKMELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2916170-A1 ESTER-GROUP-CONTAINING COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM Nissan Chemical Industries, Ltd. (JP) 2015-09-09 EP disclosed
EP-0514942-B1 Novel benzopyran derivatives and processes for the preparation thereof KOREA RES INST CHEM TECH (KR) 1997-03-05 EP disclosed
US-5493029-A USEFUL IN TREATING ASTHMA AND HYPERTENSION KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-02-20 US disclosed
EP-0514935-B1 Novel benzopyran derivatives and processes for the preparation thereof KOREA RES INST CHEM TECH (KR) 1995-11-08 EP disclosed
US-5300511-A Spiro-benzopyran derivatives and useful for treating asthma and hypertension KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1994-04-05 US disclosed
US-5236935-A Hypotensive agents KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-08-17 US disclosed
EP-0514942-A1 Novel benzopyran derivatives and processes for the preparation thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-11-25 EP disclosed
EP-0514935-A1 Novel benzopyran derivatives and processes for the preparation thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-11-25 EP disclosed