Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.44 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8798710 | 0.99 | PARP1 (0.52) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL9485325 | 0.90 | PARP1 (0.51) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL8798234 | 0.86 | PRKCD (0.58) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL8800099 | 0.83 | PARP1 (0.50) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| Maleic Acid SCHEMBL8799129 | 0.81 | PARP1 (0.43) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL8799164 | 0.81 | PARP1 (0.48) | PARP1PRKCDPRKCGPRKCBPRKCA | |
| SCHEMBL6862141 | 0.80 | PRKCD (0.53) | PRKCDPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL5037320 | 0.76 | TSHR (0.57) | PARP1HSD17B10HTR2AHTR2CHRH1 | |
| SCHEMBL8800073 | 0.76 | DRD4 (0.45) | PARP1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9483531 | 0.76 | PARP1 (0.54) | PARP1PRKCDPRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525584-B1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | SOLVAY PHARM GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5272143-A | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1993-12-21 | — | — | US | disclosed |
| EP-0525584-A1 | 6-Oxo-azepinoindole derivatives, process and intermediates for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |