Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | HTR2B | P41595 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798234 | 0.78 | PRKCD (0.58) | PARP1MAPTGAAKDM4EMEN1 | |
| SCHEMBL1252254 | 0.76 | GAA (0.62) | PARP1MAPTGAA | |
| SCHEMBL1252255 | 0.76 | GAA (0.62) | PARP1MAPTGAA | |
| SCHEMBL2080900 | 0.76 | GAA (0.62) | PARP1MAPTGAA | |
| SCHEMBL8798803 | 0.76 | PARP1 (0.54) | PARP1MAPTGAAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8798710 | 0.75 | PARP1 (0.52) | PARP1MAPTGAAKDM4EMEN1 | |
| Maleic Acid SCHEMBL8799129 | 0.74 | PARP1 (0.43) | PARP1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9485325 | 0.74 | PARP1 (0.51) | PARP1MAPTGAAKDM4EMEN1 | |
| SCHEMBL8800099 | 0.73 | PARP1 (0.50) | PARP1MAPTGAAKDM4EMEN1 | |
| SCHEMBL8798488 | 0.73 | PARP1 (0.44) | PARP1MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272143-A | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them | KALI-CHEMIE PHARMA GMBH (DE) | 1993-12-21 | — | — | US | disclosed |