Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.82 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798984 | 0.94 | LTB4R (0.86) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL9118541 | 0.93 | LTB4R (0.75) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799480 | 0.90 | LTB4R (1.00) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8798862 | 0.89 | LTB4R (0.78) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799932 | 0.89 | LTB4R (0.78) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799248 | 0.87 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL8801833 | 0.86 | LTB4R (0.91) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799137 | 0.85 | LTB4R (0.81) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799803 | 0.84 | LTB4R (0.82) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL8799623 | 0.84 | LTB4R (0.82) | LTB4RLTB4R2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | claimed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | claimed |
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |