Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776320 | 0.84 | ALDH1A1 (0.53) | KMT2AMEN1PKMALDH1A1TSHR | |
| SCHEMBL8992932 | 0.84 | ALDH1A1 (0.53) | KMT2APKMALDH1A1TSHRTDP1 | |
| SCHEMBL11773301 | 0.83 | HTT (0.56) | KMT2AMEN1PKMALDH1A1TDP1 | |
| SCHEMBL11772632 | 0.80 | HTT (0.49) | KMT2AMEN1PKMALDH1A1TSHR | |
| SCHEMBL18528029 | 0.79 | AR (0.55) | ALDH1A1TSHRGLAHTTLMNA | |
| SCHEMBL18528032 | 0.79 | AR (0.55) | ALDH1A1TSHRGLAHTTLMNA | |
| SCHEMBL108993 | 0.79 | KMT2A (0.62) | KMT2AMEN1PKMALDH1A1STAT3 | |
| SCHEMBL29516649 | 0.79 | KMT2A (0.62) | KMT2AMEN1PKMALDH1A1STAT3 | |
| SCHEMBL26090819 | 0.77 | MEN1 (0.49) | KMT2AMEN1ALDH1A1HTTGAA | |
| SCHEMBL19666254 | 0.77 | ALDH1A1 (0.54) | KMT2APKMALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532039-B1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | BRISTOL MYERS SQUIBB CO (US) | 1997-12-03 | — | — | EP | disclosed |