Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954804 | 0.87 | FDFT1 (0.47) | FDFT1ALDH1A1MDM2 | |
| SCHEMBL6954810 | 0.87 | FDFT1 (0.47) | FDFT1ALDH1A1MDM2 | |
| SCHEMBL6952893 | 0.87 | FDFT1 (0.55) | FDFT1MDM2 | |
| SCHEMBL4116107 | 0.87 | FDFT1 (0.55) | FDFT1MDM2 | |
| SCHEMBL6954797 | 0.87 | FDFT1 (0.47) | FDFT1ALDH1A1MDM2 | |
| SCHEMBL6952888 | 0.87 | FDFT1 (0.55) | FDFT1MDM2 | |
| SCHEMBL6957815 | 0.87 | FDFT1 (0.41) | FDFT1ALDH1A1 | |
| SCHEMBL6957809 | 0.87 | FDFT1 (0.41) | FDFT1ALDH1A1 | |
| SCHEMBL6957819 | 0.87 | FDFT1 (0.41) | FDFT1ALDH1A1 | |
| SCHEMBL8800243 | 0.87 | FDFT1 (0.42) | FDFT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677298-A | USEFUL FOR THE PROPHYLAXIS OR THERAPY OF HYPERCHOLESTEREMIA OR CORONOARY SCLEROSIS OF MAMMALS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0645377-B1 | Benzoxazepine derivatives useful as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0645377-A1 | Benzoxazepine derivatives useful as squalene synthetase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |