Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797975 | 0.76 | EPHX2 (0.56) | DHODHKMT2AGAAMEN1RAB9A | |
| SCHEMBL8801191 | 0.74 | CNR2 (0.38) | KMT2AMEN1HTTRAB9ANPC1 | |
| SCHEMBL13789621 | 0.73 | DHODH (0.55) | DHODHMAPK1KMT2ALMNAGAA | |
| SCHEMBL31439510 | 0.70 | DHODH (0.55) | DHODHKMT2ALMNAGAAMEN1 | |
| SCHEMBL18640737 | 0.69 | DHODH (0.54) | DHODHKMT2ALMNAGAAMEN1 | |
| SCHEMBL1185073 | 0.69 | HTT (0.52) | DHODHMAPK1KMT2ALMNAGAA | |
| SCHEMBL288085 | 0.68 | DHODH (0.60) | DHODHMAPK1KMT2ALMNAGAA | |
| SCHEMBL18640723 | 0.68 | MEN1 (0.60) | DHODHKMT2ALMNAMEN1HTT | |
| SCHEMBL8604699 | 0.68 | DHODH (0.64) | DHODHKMT2ALMNAGAAMEN1 | |
| SCHEMBL18640728 | 0.68 | DHODH (0.64) | DHODHMAPK1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |