Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569274 | 0.76 | EPHX2 (0.51) | ALDH1A1P2RX7RAB9AKMT2AMEN1 | |
| SCHEMBL8799028 | 0.74 | DHODH (0.41) | ALDH1A1P2RX7HTTRAB9AMAPT | |
| SCHEMBL8798277 | 0.69 | NPC1 (0.41) | CNR2P2RX7HTTRAB9AKMT2A | |
| SCHEMBL4516287 | 0.67 | HCRTR1 (0.42) | CNR2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL7567740 | 0.67 | KMT2A (0.42) | P2RX7HTTRAB9AKMT2AMEN1 | |
| SCHEMBL8801188 | 0.67 | CNR2 (0.38) | CNR2ALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL8797975 | 0.65 | EPHX2 (0.56) | ALDH1A1P2RX7RAB9AKMT2AMEN1 | |
| SCHEMBL13789621 | 0.64 | DHODH (0.55) | ALDH1A1HTTRAB9AMAPTKMT2A | |
| SCHEMBL7493834 | 0.64 | KMT2A (0.65) | ALDH1A1HTTRAB9AMAPTKMT2A | |
| SCHEMBL7505880 | 0.63 | SGMS2 (0.45) | ALDH1A1P2RX7RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |