Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 17/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799079 | 1.00 | SLC10A2 (0.37) | SLC10A2TACR1ADRB2HTR1AADRA2A | |
| SCHEMBL8380393 | 0.82 | SLC10A2 (0.52) | SLC10A2 | |
| SCHEMBL8380396 | 0.82 | SLC10A2 (0.52) | SLC10A2 | |
| SCHEMBL8239482 | 0.82 | SLC10A2 (0.52) | SLC10A2 | |
| SCHEMBL8200621 | 0.82 | SLC10A2 (0.52) | SLC10A2 | |
| SCHEMBL8239487 | 0.82 | SLC10A2 (0.52) | SLC10A2 | |
| SCHEMBL8805763 | 0.79 | SLC10A2 (0.54) | SLC10A2 | |
| Hydrochloric Acid SCHEMBL8204275 | 0.79 | SLC10A2 (0.54) | SLC10A2 | |
| SCHEMBL8692214 | 0.77 | SLC10A2 (0.46) | SLC10A2 | |
| SCHEMBL8377523 | 0.76 | SLC10A2 (0.47) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683773-B1 | HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES | WELLCOME FOUND (GB) | 1997-09-17 | — | — | EP | disclosed |