Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801758 | 0.91 | PTGS2 (0.57) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL8801529 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8801440 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8803743 | 0.80 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8800872 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL6289821 | 0.74 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL27607446 | 0.73 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7876663 | 0.73 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5205066 | 0.73 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5593912 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | claimed |