Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799898 | 0.90 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL9085831 | 0.90 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL8798977 | 0.87 | SIGMAR1 (0.57) | SIGMAR1F10 | |
| SCHEMBL8799808 | 0.87 | SIGMAR1 (0.57) | SIGMAR1F10 | |
| SCHEMBL8798693 | 0.87 | SIGMAR1 (0.57) | SIGMAR1F10 | |
| SCHEMBL8798326 | 0.86 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL8798538 | 0.86 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL8799641 | 0.86 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL8800626 | 0.86 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL7486541 | 0.85 | SIGMAR1 (0.55) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635505-B1 | 4-Aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GMBH (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5561145-A | 4-aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | disclosed |
| EP-0635505-A1 | 4-Aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GmbH (DE) | 1995-01-25 | — | — | EP | disclosed |