SCHEMBL8799441 — predicted protein targets

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	PPARG	P37231	15/20	0.45

▸	PPARA	Q07869	13/20	0.45

▸	KDR	P35968	1/20	0.44

▸	FFAR1	O14842	1/20	0.41

▸	MAPT	P10636	3/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8799445	1.00	PPARG (0.45)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL8341031	0.84	PPARG (0.54)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL6973022	0.82	PPARG (0.47)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL8337047	0.82	PPARG (0.47)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL8336444	0.81	PPARG (0.46)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL8340189	0.78	KDR (0.60)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL10367831	0.74	PPARG (0.58)	PPARGPPARA
SCHEMBL10367830	0.74	PPARG (0.58)	PPARGPPARA
SCHEMBL6970831	0.74	PPARG (0.56)	PPARGPPARAKDRFFAR1MAPT
SCHEMBL5015238	0.68	KDR (0.55)	PPARGPPARAKDRFFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0783496-A1	THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE	Takeda Chemical Industries, Ltd. (JP)	1997-07-16	—	—	EP	disclosed
WO-1996005186-A1	THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE	TAKEDA CHEMICAL INDUSTRIES, LTD. (JP)	1996-02-22	—	—	WO	disclosed