Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386480 | 0.75 | MAPT (0.48) | GAAMAPTP2RX4 | |
| SCHEMBL9848838 | 0.73 | GAA (0.35) | GAAMAPT | |
| SCHEMBL1505206 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL8554754 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL31695999 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL11428738 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL8119025 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL3113175 | 0.71 | GAA (0.48) | GAAMAPT | |
| SCHEMBL3241604 | 0.71 | MAPT (0.48) | GAAMAPTP2RX4 | |
| SCHEMBL30082351 | 0.71 | GAA (0.48) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679672-A | ANITARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0730596-A4 | BENZODIAZEPINES | MERCK & CO INC (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0730596-A1 | BENZODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014694-A1 | BENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |