SCHEMBL8799481

SCHEMBL8799481

O=C(O)CCCOc1ccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c(CCC(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.69
LTB4R2 Q9NPC1 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8799160 0.89 LTB4R (0.71) LTB4RLTB4R2
SCHEMBL8799541 0.88 LTB4R (0.72) LTB4RLTB4R2
SCHEMBL6757530 0.83 LTB4R (1.00) LTB4R
SCHEMBL8987440 0.83 LTB4R (1.00) LTB4R
SCHEMBL6760596 0.83 LTB4R (1.00) LTB4RLTB4R2
SCHEMBL8987039 0.82 LTB4R (1.00) LTB4R
SCHEMBL8799480 0.82 LTB4R (1.00) LTB4RLTB4R2
SCHEMBL8799418 0.80 LTB4R (0.87) LTB4RLTB4R2
SCHEMBL8987086 0.79 LTB4R (1.00) LTB4R
SCHEMBL8987171 0.79 LTB4R (1.00) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755381-A1 SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1997-01-29 EP claimed
WO-1995028386-A1 SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1995-10-26 WO claimed
EP-0763033-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-03-19 EP disclosed
EP-0755381-A1 SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1997-01-29 EP disclosed
WO-1995032198-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-11-30 WO disclosed
WO-1995028386-A1 SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 1995-10-26 WO disclosed