Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799248 | 0.94 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL8799718 | 0.92 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL6757554 | 0.90 | LTB4R (0.86) | LTB4RLTB4R2 | |
| SCHEMBL9118541 | 0.89 | LTB4R (0.75) | LTB4RLTB4R2 | |
| SCHEMBL8799917 | 0.88 | LTB4R (0.74) | LTB4RLTB4R2 | |
| SCHEMBL8799141 | 0.87 | LTB4R (0.70) | LTB4RLTB4R2 | |
| SCHEMBL8800385 | 0.87 | LTB4R (0.70) | LTB4RLTB4R2 | |
| SCHEMBL8800386 | 0.87 | LTB4R (0.65) | LTB4RLTB4R2 | |
| SCHEMBL8798984 | 0.87 | LTB4R (0.86) | LTB4RLTB4R2 | |
| SCHEMBL6757784 | 0.86 | LTB4R (0.72) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |