Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799259 | 0.93 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8801735 | 0.89 | LTB4R (0.51) | LTB4RLTB4R2 | |
| SCHEMBL6757561 | 0.88 | LTB4R (0.64) | LTB4RLTB4R2 | |
| SCHEMBL8799732 | 0.87 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL8800391 | 0.86 | LTB4R (0.55) | LTB4RLTB4R2 | |
| SCHEMBL8799168 | 0.85 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8800392 | 0.85 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL6757789 | 0.84 | LTB4R (0.58) | LTB4RLTB4R2 | |
| SCHEMBL8799754 | 0.84 | LTB4R (0.49) | LTB4RLTB4R2 | |
| SCHEMBL8799922 | 0.83 | LTB4R (0.61) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |