Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799075 | 1.00 | SIGMAR1 (0.60) | SIGMAR1GRM2 | |
| SCHEMBL8800469 | 0.92 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL9086861 | 0.92 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL8800192 | 0.92 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL8799296 | 0.92 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| Hydrochloric Acid SCHEMBL8799278 | 0.91 | SIGMAR1 (0.65) | SIGMAR1GRM2 | |
| SCHEMBL8799299 | 0.90 | GRM2 (0.54) | SIGMAR1GRM2 | |
| SCHEMBL8799473 | 0.89 | SIGMAR1 (0.62) | SIGMAR1GRM2 | |
| SCHEMBL9085473 | 0.89 | SIGMAR1 (0.62) | SIGMAR1GRM2 | |
| SCHEMBL8799302 | 0.89 | GRM2 (0.57) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635505-B1 | 4-Aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GMBH (DE) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997023567-A1 | PROCESS FOR PREPARING BLENDS OF POLY(ETHYLENE TEREPHTHALATE) AND POLY(ETHYLENE 2,6-NAPHTHALENEDICARBOXYLATE) | EASTMAN CHEMICAL COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |
| US-5561145-A | 4-aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | disclosed |
| EP-0635505-A1 | 4-Aryloxy- and 4-arylthiopiperidine derivatives | MERCK PATENT GmbH (DE) | 1995-01-25 | — | — | EP | disclosed |