SCHEMBL8799583

SCHEMBL8799583

CC[C@]1(CC(=O)C(F)(F)C(F)(F)F)CS(=O)(=O)c2cc(OC)c(OC)cc2[C@H](c2ccccc2)N1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8799361 0.88 SLC10A2 (0.67) SLC10A2
SCHEMBL8799030 0.86 SLC10A2 (0.72) SLC10A2
SCHEMBL9961466 0.86 SLC10A2 (0.84) SLC10A2
SCHEMBL1387436 0.86 SLC10A2 (0.84) SLC10A2
SCHEMBL16088329 0.86 SLC10A2 (0.84) SLC10A2
SCHEMBL8799144 0.82 SLC10A2 (0.61) SLC10A2
SCHEMBL8689142 0.82 SLC10A2 (0.81) SLC10A2
SCHEMBL8228241 0.81 SLC10A2 (0.44) SLC10A2
SCHEMBL8228239 0.81 SLC10A2 (0.44) SLC10A2
SCHEMBL2452161 0.80 SLC10A2 (1.00) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683773-B1 HYPOLIPIDAEMIC CONDENSED 1,4-THIAZEPINES WELLCOME FOUND (GB) 1997-09-17 EP claimed