Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13261931 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL3874161 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL3913002 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL849754 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL17924282 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL29612923 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL31602704 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL7013723 | 0.83 | POLB (0.58) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL10113694 | 0.81 | MAPT (0.71) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL13261932 | 0.80 | LMNA (0.53) | ALDH1A1MAPTLMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |