Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692092 | 0.72 | NPC1 (0.43) | CYP1A2CYP2C9CYP2C19HTTKDM4E | |
| SCHEMBL18740669 | 0.69 | PTGES (0.43) | CYP1A2CYP2C9CYP2C19HTTKDM4E | |
| SCHEMBL10571061 | 0.68 | HTT (0.49) | CYP1A2CYP2C9CYP2C19HTTMAPT | |
| SCHEMBL10574320 | 0.67 | TP53 (0.49) | CYP1A2CYP2C9CYP2C19HTTKDM4E | |
| SCHEMBL10572698 | 0.67 | HTT (0.46) | CYP1A2CYP2C9CYP2C19HTTMAPT | |
| SCHEMBL10574780 | 0.67 | CA12 (0.43) | CYP1A2CYP2C9CYP2C19HTTKDM4E | |
| SCHEMBL10572162 | 0.66 | MAPT (0.46) | CYP1A2CYP2C9CYP2C19HTTMAPT | |
| SCHEMBL30808062 | 0.65 | MEN1 (0.48) | CYP1A2CYP2C9CYP2C19HTTHSD17B10 | |
| SCHEMBL26767749 | 0.65 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19HTTGRIA2 | |
| SCHEMBL10572752 | 0.64 | HTT (0.51) | CYP1A2CYP2C9CYP2C19HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641789-B1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5401739-A | Benzothiadiazine derivatives | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0641789-A1 | BENZOTHIADIAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |